Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Dr Mohan Z Mani

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On Sep 2018




Prof. Somashekhar Nimbalkar

"Over the last few years, we have published our research regularly in Journal of Clinical and Diagnostic Research. Having published in more than 20 high impact journals over the last five years including several high impact ones and reviewing articles for even more journals across my fields of interest, we value our published work in JCDR for their high standards in publishing scientific articles. The ease of submission, the rapid reviews in under a month, the high quality of their reviewers and keen attention to the final process of proofs and publication, ensure that there are no mistakes in the final article. We have been asked clarifications on several occasions and have been happy to provide them and it exemplifies the commitment to quality of the team at JCDR."



Prof. Somashekhar Nimbalkar
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad
Chairman, Research Group, Charutar Arogya Mandal, Karamsad
National Joint Coordinator - Advanced IAP NNF NRP Program
Ex-Member, Governing Body, National Neonatology Forum, New Delhi
Ex-President - National Neonatology Forum Gujarat State Chapter
Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat.
On Sep 2018




Dr. Kalyani R

"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."



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Professor and Head
Department of Pathology
Sri Devaraj Urs Medical College
Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka
On Sep 2018




Dr. Saumya Navit

"As a peer-reviewed journal, the Journal of Clinical and Diagnostic Research provides an opportunity to researchers, scientists and budding professionals to explore the developments in the field of medicine and dentistry and their varied specialities, thus extending our view on biological diversities of living species in relation to medicine.
‘Knowledge is treasure of a wise man.’ The free access of this journal provides an immense scope of learning for the both the old and the young in field of medicine and dentistry as well. The multidisciplinary nature of the journal makes it a better platform to absorb all that is being researched and developed. The publication process is systematic and professional. Online submission, publication and peer reviewing makes it a user-friendly journal.
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Dr Saumya Navit
Professor and Head
Department of Pediatric Dentistry
Saraswati Dental College
Lucknow
On Sep 2018




Dr. Arunava Biswas

"My sincere attachment with JCDR as an author as well as reviewer is a learning experience . Their systematic approach in publication of article in various categories is really praiseworthy.
Their prompt and timely response to review's query and the manner in which they have set the reviewing process helps in extracting the best possible scientific writings for publication.
It's a honour and pride to be a part of the JCDR team. My very best wishes to JCDR and hope it will sparkle up above the sky as a high indexed journal in near future."



Dr. Arunava Biswas
MD, DM (Clinical Pharmacology)
Assistant Professor
Department of Pharmacology
Calcutta National Medical College & Hospital , Kolkata




Dr. C.S. Ramesh Babu
" Journal of Clinical and Diagnostic Research (JCDR) is a multi-specialty medical and dental journal publishing high quality research articles in almost all branches of medicine. The quality of printing of figures and tables is excellent and comparable to any International journal. An added advantage is nominal publication charges and monthly issue of the journal and more chances of an article being accepted for publication. Moreover being a multi-specialty journal an article concerning a particular specialty has a wider reach of readers of other related specialties also. As an author and reviewer for several years I find this Journal most suitable and highly recommend this Journal."
Best regards,
C.S. Ramesh Babu,
Associate Professor of Anatomy,
Muzaffarnagar Medical College,
Muzaffarnagar.
On Aug 2018




Dr. Arundhathi. S
"Journal of Clinical and Diagnostic Research (JCDR) is a reputed peer reviewed journal and is constantly involved in publishing high quality research articles related to medicine. Its been a great pleasure to be associated with this esteemed journal as a reviewer and as an author for a couple of years. The editorial board consists of many dedicated and reputed experts as its members and they are doing an appreciable work in guiding budding researchers. JCDR is doing a commendable job in scientific research by promoting excellent quality research & review articles and case reports & series. The reviewers provide appropriate suggestions that improve the quality of articles. I strongly recommend my fraternity to encourage JCDR by contributing their valuable research work in this widely accepted, user friendly journal. I hope my collaboration with JCDR will continue for a long time".



Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
Bengaluru.
On Aug 2018




Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
It 's a multispecialty journal, publishing high quality articles. It gives a platform to the authors to publish their research work which can be available for everyone across the globe to read. The best thing about JCDR is that the full articles of all medical specialties are available as pdf/html for reading free of cost or without institutional subscription, which is not there for other journals. For those who have problem in writing manuscript or do statistical work, JCDR comes for their rescue.
The journal has a monthly publication and the articles are published quite fast. In time compared to other journals. The on-line first publication is also a great advantage and facility to review one's own articles before going to print. The response to any query and permission if required, is quite fast; this is quite commendable. I have a very good experience about seeking quick permission for quoting a photograph (Fig.) from a JCDR article for my chapter authored in an E book. I never thought it would be so easy. No hassles.
Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".



Dr. Mamta Gupta
Consultant
(Ex HOD Obs &Gynae, Hindu Rao Hospital and associated NDMC Medical College, Delhi)
Aug 2018




Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.


Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."



Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
E-mail: drrajendrak1@rediffmail.com
On May 11,2011




Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."



Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
E-mail: ravi.dr.shankar@gmail.com
On April 2011
Anuradha

Dear team JCDR, I would like to thank you for the very professional and polite service provided by everyone at JCDR. While i have been in the field of writing and editing for sometime, this has been my first attempt in publishing a scientific paper.Thank you for hand-holding me through the process.


Dr. Anuradha
E-mail: anuradha2nittur@gmail.com
On Jan 2020

Important Notice

Original article / research
Year : 2024 | Month : January | Volume : 18 | Issue : 1 | Page : YC19 - YC22 Full Version

Cardiorespiratory Fitness in Middle-aged Men and Women through the Queens College Step Test: A Cross-sectional Study


Published: January 1, 2024 | DOI: https://doi.org/10.7860/JCDR/2024/65391.18964
Dhanush Kotian, Yogita Hatmode

1. Postgraduate Student (MPT), Department of Physiotherapy, Nitte Institute of Physiotherapy, Mangaluru, Karnataka, India. 2. Assistant Professor, Department of Physiotherapy, Nitte Institute of Physiotherapy, Mangaluru, Karnataka, India.

Correspondence Address :
Yogita Hatmode,
Deralakatte, Mangaluru, Karnataka, India.
E-mail: yogita.hathmode@gmail.com

Abstract

Introduction: Increased Body Mass Index (BMI) is associated with a decreased level of maximium oxygen uptake (VO2 max), which indirectly affects Cardiorespiratory Fitness (CRF) in young adults. Therefore, it is important to assess CRF in the middle-aged population, despite a high burden of cardiovascular risk factors in this age group. CRF refers to the circulatory system’s ability to supply oxygen to functioning muscles during continuous physical exercise. Maximum oxygen uptake (VO2 max) is the best measure of CRF and serves as the gold standard for quantifying an individual’s aerobic capacity.

Aim: To evaluate CRF in middle-aged men and women.

Materials and Methods: The present cross-sectional study conducted in the Department of Physiotheraphy, NITTE Institute of Physiotheraphy included a total of 134 subjects aged between 45 and 65 years, who were selected from Justice KS Hegde Charitable Hospital in Mangaluru, Karnataka, India. The male and female groups consisted of 67 subjects each. The study was conducted over a period of 12 months, from March 2022 to March 2023. All subjects were included based on specific inclusion criteria. VO2 max was estimated by following the Queens College Step Test (QCST) method. The Pearson’s correlation coefficient was used to examine the relationship between age, height, weight, BMI, waist-to-hip ratio, heart rate, and VO2 max. A p-value <0.05 was considered statistically significant.

Results: The mean value of VO?SUB?2#SUB# max was assessed and compared between middle-aged males (65.8±3.5 mL/kg/min) and females (46.6±1.7 mL/kg/min). It was discovered that VO2 max was significantly higher in middle-aged males than in middle-aged females (p<0.001), as indicated by heart rate changes from pretest to post-test. The mean value of BMI was compared between males (24.4±3.2) kg/m2 and females (24.4±4.9) kg/m2, and the difference was found to be statistically non significant (p-value=0.916). Similarly, the mean value of waist-to-hip ratio was compared between males (0.9±0.1) and females (0.9±0.1), and the difference was also statistically non significant (p-value=0.637).

Conclusion: Middle-aged males exhibit substantially higher VO?SUB?2#SUB# max compared to middle-aged females (p<0.001). Consequently, middle-aged females demonstrate a considerable decrease in aerobic capacity, as indicated by VO2 max, and decreased cardiovascular fitness, which serve as predictors of cardiovascular disease risk factors.

Keywords

Aerobic capacity, Cardiovascular fitness, Maximium oxygen uptake, Middle age, Physical activity

Cardiorespiratory Fitness (CRF) refers to the capacity of the circulatory system to supply oxygen to working muscles during continuous physical activity (1). The maximum amount of oxygen an individual can inhale and use to produce energy, i.e., Adenosine Triphosphate (ATP) aerobically, is known as VO2 max (2).

VO2 max is often used as a marker of physical fitness and is considered a reliable indicator of aerobic fitness (3). One practical field test for assessing individuals’ aerobic fitness is the step test, which provides an estimation of VO2 max (4). VO2 max can be calculated using either maximal or submaximal exercise tests. Walking or running tests are the most commonly used, followed by cycling and step tests (5). VO2 max is frequently estimated using prediction equations rather than direct measurements because they are less expensive and easier to perform. For males: VO2 max=111.33-(0.42×pulse rate beats/min), and for females: VO2 max=65.81-(0.1847×pulse rate beats/min) (6).

One of the global pandemics is physical inactivity, with more than 30% of adults failing to achieve a meaningful level of daily activity [7,8]. Non communicable diseases such as coronary heart disease and type 2 diabetes mellitus are major causes of death. Furthermore, physical inactivity is responsible for 6% to 10% of all deaths (9).

Moreover, low CRF is linked to an increased risk of cardiovascular disease, which contributes to adult mortality. CRF is an important aspect of health that has been shown to decline non linearly with age. Lower CRF levels are associated with a shorter life expectancy, higher healthcare costs, and poor clinical outcomes [10,11].

Measurements of body weight (anthropometry) are used in clinical settings to reflect body fat, as these measurements provide a rapid and cost-effective way to estimate body fat (12). In general, using heart rate to predict VO2 max is simple and reliable (13). Exercise testing is an important clinical tool for assessing cardiorespiratory fitness and predicting future adverse cardiovascular events (14). The QCST is a modified version of the Harvard step test, where individuals step up and down on a 16.25-inch/41.3 cm platform at a rate of 22 steps per minute for females and 24 steps per minute for males for three minutes. In the Harvard step test, individuals step up and down on a 20-inch platform for males and a 16-inch platform for females for five minutes (2).

Hence, the present study emphasises CRF in terms of maximum aerobic capacity (VO2 max) among middle-aged men and women. A previous study reported an association between increased BMI and decreased VO2 max, which indirectly affects CRF in young adults (11). Therefore, it is important to assess CRF in the middle-aged population, despite the high burden of cardiovascular risk factors in this age group. The available evidence on using the QCST procedure to estimate VO2 max in the middle-aged population is of very low certainty (15).

The QCST has high reliability and validity, is cost-effective, consumes less time, and does not require a special laboratory setting compared to other practical field tests. If this study demonstrates a significant difference in CRF between middle-aged men and women, it could highlight the importance of maintaining normal BMI and body fat percentage to improve VO2 max through physical activity, thereby preventing cardiovascular risk factors. The main aim of present study is to evaluate CRF in middle-aged men and women and to assess and compare CRF in terms of maximum aerobic capacity (VO2 max) using the QCST.

Material and Methods

The present cross-sectional study was conducted in the Department of Physiotheraphy, NITTE Institute of Physiotheraphy at Justice KS Hegde Charitable Hospital in Mangaluru, Karnataka, India. The study was carried out from March 2022 to February 2023. Ethical clearance for the study was obtained from the Institutional Ethics Committee of the Institute with reference number NIPT/IEC/Min/08/2021-22 prior to data collection.

Sample size calculation: The sample size was calculated based on the Standard Deviation (SD) of VO2 max in males (6.26) and females (3.71) (5). With a mean difference of 2.5, effect size of 0.5015, alpha error of 5%, and power of 80% for a two-sided hypothesis, the sample size in each group was determined to be 67, resulting in a total of 134 subjects. This calculation was performed using nMaster software version 2.0.

Inclusion criteria: The study included participants between the ages of 45-65 years (middle age group) who were willing to participate and screened based on the PAR-Q+ 2021 questionnaire. Both males and females without any history of previous cardiac surgeries or cardiovascular complications were included.

Exclusion criteria: Participants with knee osteoarthritis, recent lower limb fractures or surgeries, and previous history of cardiovascular complications such as myocardial infarction, coronary heart disease, diabetes mellitus, and hypertension were excluded from the study.

Study Procedure

A total of 134 eligible participants were enrolled in the study. The objective and protocol of the study were explained, and written consent was obtained from the participants. The PAR-Q+ 2021 questionnaire was used to screen the participants (16). Anthropometric data, such as age and height measured using a height meter, weight measured using a digital weighing machine, and BMI, were recorded (4). Body fat percentage was calculated using the waist-to-hip ratio, as skinfold calipers were not available. Pretest heart rate was noted. The QCST (17),(18), a modified version of the Harvard step test, was performed, where participants stepped up and down on a 16.25-inch/41.3 cm platform at a rate of 22 steps per minute for females and 24 steps per minute for males for three minutes. After completing the activity, the post-test heart rate was recorded, and VO2 max was computed using the appropriate equation (2).

Statistical Analysis

The collected data were summarised using descriptive statistics, including frequency, percentage, mean, and standard deviation. The independent sample t-test was used to compare age, height, weight, BMI, waist-to-hip ratio, and VO2 max between males and females. The paired t-test was used for the pre-to-post-test comparison of heart rate. The Pearson’s correlation coefficient was used to determine the relationship between age, height, weight, BMI, waist-to-hip ratio, heart rate, and VO2 max. A p-value less than 0.05 was considered significant. Data were analysed using Statistical Packages for Social Sciences (SPSS) software (SPSS Inc.; Chicago, IL) version 26.0.

Results

The present study was conducted among 134 middle-aged individuals, including 67 (50%) males and 67 (50%) females. The participants’ ages ranged from 45 to 65 years, with a mean of 54.9±5.0 years. Height ranged from 142 to 186 cm, with a mean of 160.6±9.1 cm. Weight ranged from 32 to 94.3 kg, with a mean of 62.8±10.4 kg. BMI ranged from 14.4 to 35.6 kg/m2, with a mean of 24.4±4.2 kg/m2 Waist-to-hip ratio ranged from 0.49 to 1.4, with a mean of 24.4±4.2 cm. VO2 max ranged from 42 to 73.1, with a mean of 56.2±10 (Table/Fig 1).

The study revealed that the mean value of VO2 max was 65.8±3.5 mL/kg/min for middle-aged males and 46.6±1.7 mL/kg/min for females.

There was a significant difference in VO2 max between middle-aged males and females (p<0.001) (Table/Fig 2).

The paired t-test was used for the pre-to-post-test comparison of heart rate. There was a significant difference (p<0.001) in heart rate from the pretest to the post-test (Table/Fig 3).

The Pearson’s correlation coefficient was used to determine the relationships between age, height, weight, BMI, waist-to-hip ratio, heart rate, and VO2 max among males. Age was positively correlated with weight (p=0.006) and BMI (p=0.033) among males. Height was positively correlated with weight (p<0.001) and heart rate (pretest) (p=0.001). Weight was positively correlated with BMI (p<0.001) and heart rate (post-test) (p=0.028). Additionally, a positive correlation was found between BMI and waist-to-hip ratio (p=0.038) (Table/Fig 4).

The Pearson’s correlation coefficient was used to determine the relationships between age, height, weight, BMI, waist-to-hip ratio, heart rate, and VO2 max among females. Height was negatively correlated with BMI (p=0.002). Weight was positively correlated with waist-to-hip ratio (p<0.001), heart rate (pretest) (p=0.008), heart rate (post-test) (p=0.002), BMI (p<0.001), and negatively correlated with VO2 max (p=0.002). BMI was positively correlated with waist-to-hip ratio (p=0.001), heart rate (post-test) (p=0.001), and VO2 max (p=0.001). A negative correlation was found between heart rate (both pretest and post-test) and VO2 max among females (p<0.001) (Table/Fig 5).

Discussion

The middle-aged population is more susceptible to developing cardiovascular complications, which is a leading cause of mortality and morbidity worldwide. Obesity and cardiorespiratory fitness are controllable and independent risk factors for cardiovascular death. Maximal oxygen uptake (VO2 max) is the extreme amount of oxygen consumption attained during strenuous exercise. Therefore, VO2 max is widely accepted as a parameter for measuring an individual’s cardiopulmonary status (8). The QCST is one of the most widely used field tests for estimating VO2 max (16),(18).

The current study disclosed that the mean value of VO2 max for middle-aged males (65.8±3.5 mL/kg/min) and females (46.6±1.7 mL/kg/min) was assessed and compared. It was found that VO2 max was significantly higher in middle-aged males compared to middle-aged females. This suggests that a decrease in VO2 max can be a reliable indicator of reduced exercise or aerobic capacity in middle-aged females, which, in turn, can lead to further cardiovascular complications.

Similar results were demonstrated by Koju B et al., who conducted a study comparing the mean value of VO2 max in young adult males and females. They found that VO2 max was significantly higher in young adult males compared to young adult females. The study mainly conducted on medical students and aimed to assess and compare the effect of various physical and academic parameters on cardiorespiratory fitness, specifically in terms of maximum aerobic capacity (VO2 max) (11).

In the present study, the mean values of pretest (96.0±8.1) and post-test (105.9±8.0) heart rates were compared, and a significant difference was found between the two. The heart rate showed a significant increase after the strenuous exercise. The present finding is consistent with the study by Leeper NJ et al., who suggested that the heart rate increase at peak exercise is strongly associated with heart rate recovery, which is estimated using treadmill testing and maximum exercise exertion (19).

The current study compared the mean values of BMI in males (24.4±3.2) kg/m2 and females (24.4±4.9) kg/m2 and found no significant difference between the BMI of middle-aged males and females. BMI is a commonly used anthropometric tool for assessing body fat percentage. However, it has limitations in differentiating between fat mass and muscle mass in individuals.

A study conducted by Singh SK and Dubey PP analysed and compared BMI among males and females in the age group of 15 to 75 years. Their findings revealed a considerable difference in BMI between males and females. They also found a higher proportion of females with high BMI compared to males across all age groups (20).

The current research compared the mean values of waist-to-hip ratio in males (0.9±0.1) and females (0.9±0.1) and found no statistically significant difference. Waist-to-hip ratio is an anthropometric measurement used to assess body fat distribution in individuals.

A review conducted by Stevens J et al., conducted a review on association between gender, age, and waist circumference. The review revealed that waist circumference and waist-to-hip ratio increase with aging in both males and females. It concluded that males tend to have a larger increase in waist circumference with weight gain compared to females (21).

In present study, there was a significant increase in aerobic capacity, as measured by VO2 max, in middle-aged males compared to middle-aged females. The reduced maximum aerobic capacity in middle-aged females may be attributed to the fact that most of the female participants in the current study were in the age group of 45 to 65 years, which is the menopausal age group. Postmenopausal women experience physiological changes that can impact the cardiovascular system and potentially decrease exercise or aerobic capacity in middle-aged females.

Limitation(s)

The biomechanical characteristic such as height varies among individuals, with taller people having a potential advantage in performing QCST compared to individuals with shorter stature.

Conclusion

It was indicated that there was a statistically significant difference between the pretest and post-test heart rates, indicating a change in heart rate from pretest to post-test. Furthermore, no significant difference was found in BMI or waist-to-hip ratio between both genders. The study concluded that VO2 max in middle-aged males is significantly higher than in middle-aged females. Hence, middle-aged females experience a considerable decrease in aerobic capacity, which is reflected in their lower VO2 max and decreased cardiovascular fitness. This decrease in cardiovascular fitness serves as a predictor of cardiovascular disease risk factors. However, individuals can improve their VO2 max by indulging in regular physical activity and exercise, which can ultimately lead to increased cardiovascular fitness.

References

1.
Khurana E OER. Determination of cardiovascular fitness in young healthy medical students. IAIM. 2016;3(10):74-78.
2.
Andrade CH, Cianci RG, Malaguti C, Corso SD. The use of step tests for the assessment of exercise capacity in healthy subjects and in patients with chronic lung disease. J Bras Pneumol. 2012;38(1):116-24. [crossref][PubMed]
3.
Zeiher J, Ombrellaro KJ, Perumal N, Keil T, Mensink GBM, Finger JD. Correlates and determinants of cardiorespiratory fitness in adults: A systematic review. Sports Med Open. 2019;5(1):39. [crossref][PubMed]
4.
Seulgi-Choi, Sim S, Minjin-Kim, Hong JH, Lee DY, Yu JH. Affect of different intensities of queens college step tests on cardiopulmonary function and body composition in students. Medico Legal Update. 2019;19(2):441-46. [crossref]
5.
Nabi T, Rafiq N, Qayoom O. Assessment of cardiovascular fitness [VO2 max] among medical students by Queens College step test. Int j Biomed Adv Res. 2015;6(5):418-21.
6.
Lippincott Williams & Wilkins; American College of Sports Medicine, editor. ACSM’s health-related physical fitness assessment manual. 2013 Jan 21. Vol. 11th. 2021.
7.
Hallal PC, Andersen LB, Bull FC, Guthold R, Haskell W, Ekelund U. Global physical activity levels: Surveillance progress, pitfalls, and prospects. The Lancet. 2012;380(9838):247-57. [crossref][PubMed]
8.
Bachmann JM, DeFina LF, Franzini L, Gao A, Leonard DS, Cooper KH, et al. Cardiorespiratory Fitness in Middle Age and Health Care Costs in Later Life. J Am Coll Cardiol. 2015;66(17):1876-85. [crossref][PubMed]
9.
Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT. Effect of physical inactivity on major non-communicable diseases worldwide: An analysis of burden of disease and life expectancy. The Lancet. 2012;380(9838):219-29. [crossref][PubMed]
10.
Sui X, LaMonte MJ, Blair SN. Cardiorespiratory fitness and risk of nonfatal cardiovascular disease in women and men with hypertension. Am J Hypertens. 2007;20(6):608-15. [crossref][PubMed]
11.
Koju B, Chaudhary S, Shrestha A, Joshi LR. The cardio-respiratory fitness in medical students by Queen’s College step test: A cross-sectional study. Journal of Lumbini Medical College. 2019;7(1)29-33. [crossref]
12.
Setty P, Padmanabha BV, Doddamani BR. Correlation between obesity and cardio respiratory fitness. Int J Med Sci Public Health. 2013;2(2):300-04. [crossref]
13.
Plowman SA SD. The cardiovascular system. In: Exercise Physiology for Health, Fitness and Performance. 2014;4.
14.
Cooney JK, Moore JP, Ahmad YA, Jones JG, Lemmey AB, Casanova F, et al. A simple step test to estimate cardio-respiratory fitness levels of rheumatoid arthritis patients in a clinical setting. Int J Rheumatol. 2013;2013:174541. [crossref][PubMed]
15.
Warburton D, Jamnik V, Bredin S, Shephard R, Gledhill N. The 2021 physical activity readiness questionnaire for everyone (PAR-Q+) and electronic physical activity readiness medical examination (ePARmed-X+): 2021 PAR-Q+. The Health & Fitness Journal of Canada. 2021;14(1):83-87.
16.
Misra A. Ethnic-specific criteria for classification of body mass index: A perspective for Asian Indians and American Diabetes Association position statement. Diabetes Technology & Therapeutics. 2015;17(9):667-71. [crossref][PubMed]
17.
Shamsi MM, Alinejad HA, Ghaderi M, Badrabadi KT. Queen’s college step test predicted VO2max: The effect of stature. Annals of Biological Research. 2011;2(6):371-77.
18.
Varghese RS, Dangi A, Varghese A. VO 2 Max normative values using queen’s college step test in healthy urban indian individuals of age group 20-50 years. Int J Sci Res. 2020;9(6):803-06.
19.
Leeper NJ, Dewey FE, Ashley EA, Sandri M, Tan SY, Hadley D, et al. Prognostic value of heart rate increase at onset of exercise testing. Circulation. 2007;115(4):468-74. [crossref][PubMed]
20.
Singh SK, Dubey PP. A comparative analysis of BMI among males and females aged between 15-75 Years. International Journal of Contemporary Medical Research. 2018;5(1):1-3.
21.
Stevens J, Katz EG, Huxley RR. Associations between gender, age and waist circumference. Eur J Clin Nutr. 2010;64(1):06-15.[crossref][PubMed]

DOI and Others

DOI: 10.7860/JCDR/2024/65391.18964

Date of Submission: May 12, 2023
Date of Peer Review: Jul 25, 2023
Date of Acceptance: Nov 26, 2023
Date of Publishing: Jan 01, 2024

AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. NA

PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: May 15, 2023
• Manual Googling: Aug 23, 2023
• iThenticate Software: Nov 22, 2023 (11%)

ETYMOLOGY: Author Origin

EMENDATIONS: 7

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